Publications

12.  Chenoweth DM, Harki DA, and Dervan PB. Oligomerization route to Py-Im polyamide macrocycles. Org. Lett. 2009, 11, 3590-3593.

11.  Chenoweth DM, Harki DA, Phillips JW, Dose C, and Dervan PB. Cyclic pyrrole-imidazole polyamides targeted to the androgen response element. J. Am. Chem. Soc. 2009, 131, 7182-7188.

10.  Chenoweth DM, Harki DA, and Dervan PB. Solution-phase synthesis of pyrrole-imidazole polyamides. J. Am. Chem. Soc. 2009, 131, 7175-7181.

9.  Harki DA, Satyamurthy N, Stout DB, Phelps ME, and Dervan PB. In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography. Proc. Natl. Acad. Sci. USA 2008, 105, 13039-13044.

8.  Zamyatkin DF, Parra F, Martín Alonso JM, Harki DA, Peterson BR, Grochulski P, and Ng KKS. Structural insights into mechanisms of catalysis and inhibition in Norwalk virus polymerase. J. Biol. Chem. 2008, 283, 7705-7712.

7.  Graci JD, Too K, Smidansky ED, Edathil JP, Barr EW, Harki DA, Galarraga JE, Bollinger Jr. JM, Peterson BR, Loakes D, Brown DM, and Cameron CE. Lethal mutagenesis of picornaviruses with N6-modified purine nucleoside analogues. Antimicrob. Agents Chemother. 2008, 52, 971-979.

6.  Graci JD, Harki DA, Korneeva VS, Edathil JP, Too K, Franco D, Smidansky ED, Paul AV, Peterson BR, Brown DM, Loakes D, and Cameron CE. Lethal mutagenesis of poliovirus mediated by a mutagenic pyrimidine analogue. J. Virol. 2007, 81, 11256-11266.

5.  Harki DA, Graci JD, Edathil JP, Castro C, Cameron CE, and Peterson BR. Synthesis of a universal 5-nitroindole ribonucleotide and incorporation into RNA by a viral RNA-dependent RNA polymerase. ChemBioChem 2007, 8, 1359-1362.

4.  Harki DA, Graci JD, Galarraga JE, Chain WJ, Cameron CE, and Peterson BR. Synthesis and antiviral activity of 5-substituted cytidine analogues: identification of a potent inhibitor of viral RNA-dependent RNA polymerases. J. Med. Chem. 2006, 49, 6166-6169.

3.  Simeonova PP, Hulderman T, Harki D, Luster MI. Arsenic exposure accelerates atherogenesis in apolipoprotein E-/- mice. Environ. Health Perspect. 2003, 111, 1744-1748.

2.  Harki DA, Graci JD, Korneeva VS, Ghosh SKB, Hong Z, Cameron CE, and Peterson BR. Synthesis and antiviral evaluation of a mutagenic and non-hydrogen bonding ribonucleoside analogue: 1-β-D-ribofuranosyl-3-nitropyrrole. Biochemistry 2002, 41, 9026-9033.

1.  Simeonova PP, Wang S, Toriuma W, Kommineni V, Matheson J, Unimye N, Kayama F, Harki D, Ding M, Vallyathan V, Luster MI. Arsenic mediates cell proliferation and gene expression in the bladder epithelium: association with activating protein-1 transactivation. Cancer Res. 2000, 60, 3445-3453.